Nanotech 2014 Vol. 2
Nanotech 2014 Vol. 2
Nanotechnology 2014: MEMS, Fluidics, Bio Systems, Medical, Computational & Photonics

Inkjets, Micro & Nano Fluidics Chapter 2

Cell Detection and Discrimination by a Microfluidic-Integrated Broadband Microchamber

Authors: A. Denzi, F. Apollonio, M. Liberti, M. Caterina, Y. Ning, C. Multari, C. Palego, X. Cheng, J.C.M. Hwang

Affilation: Lehigh University, United States

Pages: 101 - 104

Keywords: broadband microchamber, microfludics, biosensor, cell detection

In the last years, the development of broadband microwave sensors for cell detection has become a great challenge. In this work, a broadband microchamber integrated with microfluidics is used for cell detection in the GHz range. Measurements of scattering parameters have been carried out, demonstrating the capability of the device to discriminate different number of cells between the electrodes. Stable and reliable results on Jurkat cell solutions have been achieved. An equivalent circuit model, dependent on the number of cells trapped within the channel, has been extracted from the experimental data sets. We demonstrate the possibility to detect and isolate the electrical contribution of biological cells.

ISBN: 978-1-4822-5827-1
Pages: 570
Hardcopy: $209.95