Nanotech 2012 Vol. 2
Nanotech 2012 Vol. 2
Nanotechnology 2012: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational (Volume 2)

Micro & Nano Fluidics Chapter 5

Uncoil long DNA molecules in nanoposts array

Authors: J. Wu, G. Shao, J. Choi, F.I. Uba, S.A. Soper, S. Park

Affilation: Louisiana State Univ., United States

Pages: 380 - 383

Keywords: nanoposts, nanopillar array, uncoil DNA, stretch DNA

A nanoposts array was fabricated on a PMMA based nanofluidic chip by nanoimprinting lithography. The electrophoresis of Lambda and T4 DNA in the nanoposts was studied. A periodical stretching and recoiling motion was observed. Each period can be divide into unravel, unhook and recoil phase. Physical models for each phase were set up and compared with experimental results. DNA molecules were stretched up to 97% of its contour length in the nanoposts array and an observation duration of more than 1.5 sec was achieved by the nanoposts array.

ISBN: 978-1-4665-6275-2
Pages: 878
Hardcopy: $209.95

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