Cellesi F.
University of Manchester, UK
Keywords: dopamine, hybrid bionanomaterials, polymer shell, TiO2 nanoparticles
We proposed a synthetic strategy for producing hybrid bionanomaterials based on nanocrystalline TiO2 and catechol-grafted polymers. A sol-gel process in organic solvent was developed to grow TiO2 nanocrystals of highly controlled size and surface chemistry, and easily redispersible in water. A bio-inspired approach was then used to graft hydrophilic polymers on the TiO2 nanoparticles, utilising terminal catechol groups as chelating enediol ligands. These polymer-coated nanoparticles showed a safe cytotoxic profile and provide interesting advantages for applications in diagnostics, cell targeting and immunostimulation.
Journal: TechConnect Briefs
Volume: 3, Nanotechnology 2011: Bio Sensors, Instruments, Medical, Environment and Energy
Published: June 13, 2011
Pages: 279 - 282
Industry sectors: Advanced Materials & Manufacturing | Medical & Biotech
Topic: Biomaterials
ISBN: 978-1-4398-7138-6