Nanotech 2008 Vol. 2
Nanotech 2008 Vol. 2
Nanotechnology 2008: Life Sciences, Medicine & Bio Materials - Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, Volume 2

Drug & Gene Delivery Systems Chapter 4

How much advantage do Nanoscale Phenomena afford for Pulmonary Delivery?

Authors: N. Walji, M. Thanou, N. Quirke

Affilation: Imperial College London, United Kingdom

Pages: 405 - 406

Keywords: nanoparticle, diffusion, biological barriers, multiple particle tracking

Although claims of improved performance due to nanoscale phenomena are made on a daily basis, exactly how much advantage can be afforded by nanotechnology for specific medical applications is quantitatively unknown. It is generally suggested that the smaller the size the better the targeting and distribution effect, however the exact relationship between nanoparticle size and diffusivity through biological membranes is unknown. Diffusivity has traditionally been related to particle size via the Stoke-Einstein equation, which states that diffusion is inversely proportional to particle radius. It has been hypothesized that nanoscale effects, acting on particles

ISBN: 978-1-4200-8504-4
Pages: 808
Hardcopy: $159.95

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