Nanotech 2007 Vol. 3
Nanotech 2007 Vol. 3
Technical Proceedings of the 2007 NSTI Nanotechnology Conference and Trade Show, Volume 3

Micro and Nano Fluidics Chapter 4

A Microfluidic Mixer for Chaotic Mixing of Magnetic Particles

Authors: M. Zolgharni, S.M. Azimi, M.R. Bahmanyar and W. Balachandran

Affilation: Brunel University, United Kingdom

Pages: 336 - 339

Keywords: microfluidic, chaotic mixing, magnetic particles

Magnetic isolation of specific biological entities through utilizing super-paramagnetic micro-particles has been of great interest in both bench-top and microfluidic platforms. Since the magnetic particles and target entities are suspended in separate fluids, prior to separation of the labelled-cell/particle complex from contaminants, magnetic particles must be distributed into the bio-fluid containing target entity through a mixing process. In bench-top protocols, this is done using conventional turbulent mixing techniques. However, in micro-scale devices where Reynolds number is often less than 1, mixing is not a trivial task due to absence of turbulence. While separation of particles in microdevices based on magnetic forces has been reported by different researchers, there are only a few prototypes developed for mixing of particles in microscale. We present a study on chaotic mixing of magnetic particles into a bio-fluid in order to evaluate the efficiency of the mixer in capturing the target cells with particles.

ISBN: 1-4200-6184-4
Pages: 732
Hardcopy: $139.95

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