Nanotech 2007 Vol. 2
Nanotech 2007 Vol. 2
Technical Proceedings of the 2007 NSTI Nanotechnology Conference and Trade Show, Volume 2

Drug Delivery Chapter 5

Specific targeting and delivery of virus envelope-coated nanoparticle cargoes into receptor-bearing cells and subcellular compartments.

Authors: A.C. Moore, A.A. Kolokoltsov and R.A. Davey

Affilation: University of Texas Medical Branch, United States

Pages: 370 - 373

Keywords: virus, cell targeting, membrane penetration, drug delivery

We build on our recently reported work in Nano letters describing coating of nanoparticle cargoes with virus envelope proteins to show that the method works for viruses other than ecotropic murine leukemia viruses. We also track the virus-envelope coated nanoparticles into cells using real-time microscopy on live cells. We discuss the potential benefits of using this method to target drugs to specific cells and subcellular compartments.

ISBN: 1-4200-6183-6
Pages: 838
Hardcopy: $139.95