Fabrication of Photonic Transfer DNA-Quantum Dot Nanostructures

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Fabrication of Photonic Transfer DNA-Quantum Dot Nanostructures M. J. Heller, B. Sullivan and D. Dehling University of California San Diego; Departments of Bioengineering/Electrical and Computer Engineering; PFBE Bldg, Rm 429: La Jolla CA 92093; 858-822-5699; mheller@bioeng.ucsd.edu The primary objective of our research work is to develop nanofabrication technology which will allow functionalized nanostructures to be hierarchically self-assembled into higher-order 2D and 3D nanophotonic and nanoelectronic structures and devices. Our work involves developing nanofabrication techniques to carry out the selective functionalization of nanocomponents (quantum dots) with DNA. More recently, quantum dots (7-8nm) have been selectively functionalized with DNA oligonucleotide sequences in such a way that a significant portion of the Q-dots have their DNA sequences oriented in roughly polar positions. In this work two sets of quantum-dots with complementary DNA sequences were prepared and then hybridized together. Results showed that in addition to agglomerations of Q-dots into larger 3D structures, a number of long linear assemblies of Q-dots were also formed. These results represent a first level of success in carrying out the self-assembly of the DNA-Q-dot units into higher-order structures. Unfortunately, the stoichiometric methods used to produce such structures are time consuming and unreliable. Thus, the further objective of our work is to now develop more viable technologies for the hierarchically self-assembly of DNA nanostructures. This work now involves the development of electric field base assembly platforms containing electronically addressable locations by which DNA nanostructures (quantum dots) may be selectively positioned, oriented and assembled into linear nanophotonic wires.

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Journal: TechConnect Briefs
Volume: 1, Technical Proceedings of the 2005 NSTI Nanotechnology Conference and Trade Show, Volume 1
Published: May 8, 2005
Pages: 769 - 772
Industry sectors: Advanced Materials & Manufacturing | Personal & Home Care, Food & Agriculture
Topic: Personal & Home Care, Food & Agriculture
ISBN: 0-9767985-0-6