Molecular Imaging is the 2nd largest independent SPM producer and the only supplier of SPMs with scanners separated from the sample environment . The PicoPlus™ operates as a Stand alone, Environmental, or Electrochemical SPM or integrated with an Inverted Light Microscope. The PicoPlus operates to atomic scale on inverted light microscopes and offers more closed loop options than any other supplier. Interchangeable tip modules provide contact, acoustic mode, patented MAC mode for soft samples in fluid, LFM, CSAFM, EFM, Kelvin probe, Pulsed Force, Force/Distance, Magnetic Force, and STM imaging modes. All MI systems can operate with fluids such as solvents and acids, have flow through capabilities and temperature ranges from –30 to +250C.