Nano Science and Technology Institute
Nanotech 2013 Vol. 3
Nanotech 2013 Vol. 3
Nanotechnology 2013: Bio Sensors, Instruments, Medical, Environment and Energy (Volume 3)
Chapter 3: Materials for Drug & Gene Delivery

NanoBandage for Controlled Release of Topical Therapeutics

Authors:M. Patchan, X. Calderon-Colon, J. Benkoski, M. Theodore, H. Le, B. Fuller, N. Boggs, A. Nelson, L. Garza, K. Sarkar, G. Brandacher, J. Patrone
Affilation:The Johns Hopkins University Applied Physics Laboratory, US
Pages:255 - 258
Keywords:nanoparticle, drug delivery, bandage, cellulose
Abstract:Burn injuries, trauma, and surgical procedures result in complex wounds, which can lead to pain, infection, and scarring. Management of complex wounds remains a critical challenge for the medical community and effective, localized treatments are limited. Recent advancements in nanotechnology offer a unique opportunity to deliver therapeutics to wounds and improve healing. The goal of our work is to combine nontoxic, biodegradable nanomaterials with therapeutics in order to design a topical drug delivery system for controlled release into skin. In this study we demonstrate the potential of combining solid lipid nanoparticles (SLNs) and bacterial cellulose into a novel system for controlled topical drug delivery.
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