Authors: F. Cellesi
Affilation: University of Manchester, United Kingdom
Pages: 279 - 282
Keywords: hybrid bionanomaterials, TiO2 nanoparticles, dopamine, polymer shell
We proposed a synthetic strategy for producing hybrid bionanomaterials based on nanocrystalline TiO2 and catechol-grafted polymers. A sol-gel process in organic solvent was developed to grow TiO2 nanocrystals of highly controlled size and surface chemistry, and easily redispersible in water. A bio-inspired approach was then used to graft hydrophilic polymers on the TiO2 nanoparticles, utilising terminal catechol groups as chelating enediol ligands. These polymer-coated nanoparticles showed a safe cytotoxic profile and provide interesting advantages for applications in diagnostics, cell targeting and immunostimulation.