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 | Nanotech 2006 Vol. 2
Technical Proceedings of the 2006 NSTI Nanotechnology Conference and Trade Show, Volume 2
Chapter 1: Cancer Nanotechnology |
| | Functionalization of Magnetite (Fe3O4) Nanoparticles for Cancer Treatment | | Authors: | A.P. Herrera, H.L. Rodríguez, M. Torres-Lugo and C. Rinaldi | | Affilation: | University of Puerto Rico-Mayagüez, US | | Pages: | 75 - 78 | | Keywords: | magnetocytolysis, magnetie, dextran, CaCo-2 cell culture | | Abstract: | We have studied the synthesis of magnetite (Fe3O4) nanoparticles functionalized with crosslinked dextran for magnetocytolysis application using human colon cancer cells (CaCo-2). Size of the magnetite nanoparticles was determined by SQUID, XRD, and TEM measurements, yielding a value of 7-9 nm. Magnetite/crosslinked dextran nanoparticles were found to be non cytotoxic to CaCo-2 cells in the absence of an AC magnetic field. Application of 1.0 kHz 3.0 kA/m magnetic field resulted in a reduction in cell viability to 40 % after 45 min of application. | | ISBN: | 0-9767985-7-3 |
| Pages: | 893 |
| Hardcopy: | $185.00 |
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