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 | Nanotech 2005 Vol. 1
Technical Proceedings of the 2005 NSTI Nanotechnology Conference and Trade Show, Volume 1
Chapter 2: Medical Applications |
| | Intracellular Uptake of Folate Receptor Targeted Superparamagnetic Nanoparticles for Enhanced Tumor Detection by MRI | | Authors: | C. Sun, O. Veiseh, N. Kohler, J. Gunn, D. Lee, R. Sze, A. Hallahan and M. Zhang | | Affilation: | University of Washington, US | | Pages: | 74 - 77 | | Keywords: | magnetic resonance imaging, contrast agent, iron oxide nanoparticles, PEG, folic acid, tumor imaging | | Abstract: | Tumor specific superparamagnetic nanoparticle conjugates are currently being developed as targeting-contrast agents for magnetic resonance imaging (MRI). The application of such “smart” molecular imaging probes will have a significant clinical impact as a non-invasive method of cancer detection and diagnosis. In this study, we examine the vitamin folic acid (FA) as a targeting agent for the delivery of superparamagnetic nanoparticles to specific tumor cells in vitro. Results from this study suggest that the synthesized FA-superparamagnetic nanoparticle conjugates can be used to target specific tumor cells for detection by MRI. | | ISBN: | 0-9767985-0-6 |
| Pages: | 844 |
| Hardcopy: | $165.00 |
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| Order: | Mail/Fax Form |
| Special: | 3 CD Set — 15% off with Free Shipping |
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