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Biomarkers & Nanoparticles Committee

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Committee Chairs

  • Srinivas Iyer , Los Alamos National Laboratory

Annual Symposium Synopsys

Nanodevices and nanoparticles enable study of a wide range of biological phenomena extending from protein-protein interaction mapping to cancer detection in intact animals and man. Recent advances in materials science, in particular the development of functionalized nanoparticles, united with advances in molecular imaging research, provide the impetus for the present explosion in nanobiotechnology imaging research.

Key to those advances is the emergence of functionalized nanoparticles, particularly quantum dots (QDs) that can be targeted specifically to receptors, enzymes, transporters and other molecules of biological importance that can interact at the cellular level. Additionally, over the last five years there has been a proliferation of high-resolution devices for in vivo imaging in animal models of human disease and high-throughput, i.e., microarray and combinatorial, techniques for generating new diagnostic and therapeutic targets and probes.

Nanotechnology in the Life-sciences is omnipresent. Several biological systems operate at the nanoscale with remarkable precision and regulation. A fine example is that of biomolecular motor proteins, designed by nature to carry out critical functions in the cell. Most of the properties of these proteins are nanoscale, be they size or time of operation. While systems such as motors have been isolated, modified and studied in detail at the biochemical level, much needs to be done at the level of hybrid structures with interfaces to inorganic materials. Further, scaling laws need to be understood in order to bridge between single molecules and higher order devices or architectures.

A similar situation is encountered with biomaterials, another area with tremendous application potential. Alongwith these topics, this symposium will also cover the equally important area of biomolecular analysis, which has reached new levels of sensitivity, precision and resolution due to advances in other sciences. Thus, topics scuh as fluidics, detection methods and engineering approaches will receive enhanced attention. Drug design and delivery is poised the interface of several topics such as receptor signaling, computational modeling, targeted design, nanoscale biomaterials and toxicological profiles.

We invite submissions in each of these areas and related topics. A sample listing of pertinent topics is listed below. This is by no means an exclusive list, but aims to give a general overview of this diverse symposium topic.

Topics & Application Areas

  • Quantum Dots
  • Fullerenes
  • Lipids
  • Polymers
  • Dendrimers
  • Dendrimers
  • DNA-Gold-Nanoparticle Conjugates
  • Fluorescent & Luminescent Particles
  • Nucleic Acid Ligands (aptamers)
  • Targeted Functionalization of Nanoparticles

Submit Proposal or Comment to Committee Chair

We encourage you to participate and to submit your interest as either an Scientific Committee Member or to organize a Scientific Committee*. The NSTI will provide the infrastructure for each Industrial Committee to organize and present a focused Symposium at the annual Nanotech Conference and Trade Show (Nanotech 2008, Boston, Massachusetts, June 1-5, 2008). Details will be provide upon approval of proposal.

* All submissions will be reviewed by the NSTI Scientific Committee Chairs and a timely response will be issued.

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