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Nanotechnology Conference and Trade Show - Nanotech 2006

Conference Proceedings

Nano Medicine

Confirmed Speakers

	Challenges in Cancer Prevention, Diagnosis, and Treatment Judah Folkman, Children’s Hospital Boston, USA, (speaker biography)
	Nanodelivery: Materializing the Potential of Cancer Molecular Medicine Esther H. Chang Georgetown University Medical Center, USA, (speaker biography)
	Novel Nanostructures for Tumor-Targeted Delivery Dennis E. Discher University of Pennsylvania, USA, (speaker biography)
	Targeted Drug Delivery in Cancer Vladimir Torchilin Bouvé College of Health Sciences, Northeastern University, USA

	Delivery of Nano-medicine to Solid Tumors: Role of Tumor Physiology Rakesh K. Jain, Massachusetts General Hospital, Harvard Medical School, USA, (speaker biography)
	Molecular Imaging in Cancer James Basilion, Associate Professor, Department of Biomedical Engineering Case Western Reserve University, US, (speaker biography)
	Multifunctional Nanoparticles in Cancer Therapy Sangeeta Bhatia MIT, Brigham & Women’s Hospital, USA, (speaker biography)
	Klaus Wormuth Characterization Sciences SurModics Inc. Eden Prairie, MN US, (speaker biography)

Symposium Sessions
	Monday May 8
1:30	Fluidics: Particle & Cell Transport: Sponsored by Kodak
4:00	Cancer Nanotech - 1
6:00	Poster Session 1 and Nanotech Exhibit Reception hosted by Advance Nanotech, booth #903
	Tuesday May 9
8:30	Keynote - Nanotechnology for Cancer Prevention, Diagnosis and Treatment
10:30	Cancer Prevention, Diagnosis and Treatment through Nanotech
1:30	Cancer Prevention, Diagnosis and Treatment through Nanotech
3:30	Nanotechnology for Cancer Prevention, Diagnosis and Treatment
4:00	Poster Session 2 and Nanotech Exhibit Reception hosted by Feinstein Kean Healthcare, booth #716
	Cancer Nanotech -3
6:00	Translation of Cancer Nanotechnology - From Bench to Bedside (Panel)
	Wednesday May 10
10:30	Cancer Nanotech - 2
1:30	Nanotechnology for Drug Delivery
4:00	Nanotech for Neurology
4:00	Characterization: Drug Delivery
4:00	Bio Materials and Tissues - 1
6:00	Poster Session 3 and Reception
	Characterization: Drug Delivery
	Drug Delivery
	Cellular and Molecular Dynamics
	Imaging
	Bio Materials
	Thursday May 11
8:30	Medical Imaging through Nanotechnology
10:00	Coffee Break
10:30	Bio Materials and Tissues - 2
1:30	Bio Materials and Tissues - 3

Symposium Program
	Monday May 8
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1:30	Fluidics: Particle & Cell Transport: Sponsored by Kodak	Room 203
	Session chair: Steffen Hardt, Darmstadt University, DE
1:30	Micro- and Nanofluidics: Fundamentals & Applications (invited overview presentation) S. Hardt, Darmstadt University of Technology, DE
2:00	A Lab-on-a-Chip using Magnetic Droplets (invited) U. Lehmann, V.K. Parashar, C. Vandevyver and M.A.M. Gijs, EPFL, CH (speaker biography)
2:30	Whole Blood Pumped by Laser Driven Micropump T. Ussing, L.V. Petersen, U. Krühne and L. Højslet, FluimediX, DK
2:50	Combination Ultrasonic- Dielectrophoretic Particle Traps for Particle Trapping and Sample Purification in a Microfluidic Channel O. Marina, M.D. Ward and G. Kaduchak, Los Alamos National Laboratory, US
3:10	Blood dynamics in microfabricated vessel networks A.W. Mulivor, S. Shevkoplyas, C. Sun, M.W. Bitensky and L.L. Munn, Massachusetts General Hospital, US
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4:00	Cancer Nanotech - 1	Room 207
	Session chair: Travis Earles, National Cancer Institute
4:00	Nano-Mesosphere Drug Carriers for Localized Cancer Chemotherapy E.P. Goldberg, B.A. Almond, A.R. Hadba, B.J Cuevas, A. York, I. Enriquez, University of Florida, US
4:20	Temperature-Triggered Nanotechnology for Chemotherapy: Rapid Release From Lysolipid Temperature-Sensitive Liposomes J.K. Mills and D. Needham, Duke University; presently Sterne, Kessler, Goldstein & Fox, P.L.L.C., US
4:40	Role of immunoregulators as possibility of tumor hypoxia-induced apoptosis R. Sharma, S. Kwon and C.J. Chen, Columbia University, US
5:00	Modulation of Intracellular Ceramide using Polymeric Nanoparticles to Overcome Multidrug Resistance in Tumor Cells L.E. van Vlerken, D. Shenoy, Z. Duan, M. Seiden, S. Mehta and M.M. Amiji, Northeastern University, US
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6:00	Poster Session 1 and Nanotech Exhibit Reception hosted by Advance Nanotech, booth #903	Expo Hall
	Tuesday May 9
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8:30	Keynote - Nanotechnology for Cancer Prevention, Diagnosis and Treatment	Hall D
	Session chair: Mansoor Amiji, Northeastern University
8:30	Challenges in Cancer Prevention, Diagnosis, and Therapy (invited) J. Folkman, Children’s Hospital Boston, US (speaker biography)
9:15	Delivery of Nano-medicine to Solid Tumors: Role of Tumor Physiology (invited) R.K. Jain, MGH, Harvard Medical School, US (speaker biography)
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10:30	Cancer Prevention, Diagnosis and Treatment through Nanotech	Hall D
	Session chair: Mansoor Amiji, Northeastern University
10:30	Cancer Challenges and the Role of Nanotechnology (invited) M. Seiden, Massachusetts General Hospital Cancer Center, US
11:00	Nanodelivery: Materializing the Potential of Cancer Molecular Medicine (invited) E. Chang, Georgetown University, US (speaker biography)
11:30	Novel Nanostructures for Tumor-Targeted Delivery (invited) D.E. Discher, University of Pennsylvania, US (speaker biography)
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1:30	Cancer Prevention, Diagnosis and Treatment through Nanotech	Hall D
	Session chair: Mansoor Amiji, Northeastern University
1:30	Early Cancer Detection Using Nanowires (invited) F. Patolsky, Harvard Medical School, US
2:00	Molecular Imaging in Cancer (invited) J. Basilion, Case Western Reserve Univesity, US
2:30	Targeted Drug Delivery in Cancer (invited) V. Torchilin, Northeastern University, US
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3:30	Nanotechnology for Cancer Prevention, Diagnosis and Treatment	Hall D
	Session chair: Mansoor Amiji, Northeastern University
3:30	Multifunctional Nanoparticles in Cancer Therapy (invited) S. Bhatia, Massachusetts Institute of Technology, Brigham & Women’s Hospital, US (speaker biography)
4:00	Combination Thermal Medicine and Drug Delivery in Cancer (invited) S. Nahum Goldberg, Harvard Medical School, US
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4:00	Poster Session 2 and Nanotech Exhibit Reception hosted by Feinstein Kean Healthcare, booth #716	Expo Hall
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	Cancer Nanotech -3	Expo Hall
-	The Nucleolus and Cellular Stress: Analysis by Coherent Phase Microscopy V.P. Tychinsky, A.V. Kretyshev, I.V. Klemyashov, I.V. Reshetov, T.V. Vyshenskaya and A.A. Shtil, P.A.Hertsen Moscow Research Oncological Institute, RU
-	Enhanced Accumulation of Long-Circulating Liposomes Modified with Nucleosome-Specific Monoclonal Antibody 2c5 in Various Tumors in Mice T.A. ElBayoumi and V.P. Torchilin, Northeastern University, US
-	Computer Model of Cancer Development I. Barjis, M. Sayar, J. Barjis and W. Amarrai, New York City College of Technology, US
-	Assessment of the dielectric properties of drug sensitive and resistant leukaemic cells before and after ion channel blockers using dielectrophoresis L. Duncan, H. Shelmerdine, H.M. Coley and F.H. Labeed, University of Surrey, UK
-	Rapid Detection of Multiple Myeloma using a microfluidic platform G. Kaigala, J. VanDjinkin, B.J. Taylor, C.J. Backhouse and L.M. Pilarski, University of Alberta, CA
-	A novel soluble nano dimension polyhemoglobin-tyrosinase retards the growth of Murine B16F10 Melanoma in mice B. Yu and T.M.S. Chang, McGill University, CA
-	Characterization and In Vivo Biodistribution Studies with Poly(Ethylene Glycol)-Modified Thiolated Gelatin Nanoparticles S. Kommareddy and M.M. Amiji, Northeastern University, US
-	Utilizing the Electronic Industry‘s Tricks for Transistor Fabrication for Development of New Delivery Vehicles for Nanomedicine Applications L.E. Euliss, C.M. Welch, B.W. Maynor, S.E. Gratton, J-Y Park, A.A. Pandya, E. Enlow, R.L. Juliano, K.M. Hahn and J.M. DeSimone, University of North Carolina at Chapel Hill, US
-	Injection of Molecules into Cells using a pH-Triggered Molecular Nanosyringe O.A. Andreev, S. Sandugu, D.M. Engelman and Y.K. Reshetnyak, University of Rhode Island, US
-	Nano-structured Biodegradable Ceramics for the Prevention and Treatment of Bone Caner G. Balasundaram and T.J. Webster, PURDUE UNIVERSITY, US
-	Mathematical Modeling of Chemotherapy Strategies in Vascular Tumor Growth using Nanoparticles S. Mishra, V.K. Katiyar and V. Arora, Indian Institute of Technology, Roorkee, IN
-	Tumour gene delivery -transfection efficiency and uptake process of Pegylated poly-L-lysine nanoparticles M. Walsh, M. Tangney, J.O. Larkin, R. Darcy, G.C. O’Sullivan and C.M. O’Driscoll, University College Cork, IE
-	Application of Nanomagnetic Particles in Hyperthermia Cancer Treatment S. Hayek, C-J Chen, Y. Haik and V. Hohite, Florida State University, US
-	New manganite-based mediators for self-controlled magnetic hyperthermia O.A. Shlyakhtin, Y-J Oh, V.G. Leontiev and A.A. Kuznetsov, Institute of Biochemical Physics, Russian Academy of Sciences, RU
-	Laser Heating of Sulphuretted Carbon Nanoparticles Inhibits Tumor Growth B.Ya. Kogan, R.I. Yakubovskaya, A.A. Pankratov, T.N. Andreeva, L.D. Kvacheva, A.A. Titov, V.A. Puchnova, R.A. Feysulova and G.N. Vorozhtsov, Organic Intermediates & Dyes Institute, RU
-	Cu-Ni alloy magnetic nanoparticles for hyperthermia at prescribed temperature A.A. Kuznetsov, V.G. Leontiev, V.A. Brukvin, B.Ya. Kogan, O.A. Kuznetsov and O.A. Shlyakhtin, Institute of Biochemical Physics, Russian Academy of Sciences, RU
-	Functionalization of Magnetite (Fe3O4) Nanoparticles for Cancer Treatment A.P. Herrera, H.L. Rodríguez, M. Torres-Lugo and C. Rinaldi, University of Puerto Rico-Mayagüez, US
-	Radioactive Nanocomposite Mouse Tumor Treatment M.K. Khan, S.S. Nigavekar, L. Minc, B.M. Nair, M.S.T. Kariapper, W.G. Lesniak and L.P. Balogh, Roswell Park Cancer Institute, US
-	Magnetic nanoparticle vectors: A tool for diagnosis and therapy D. Nagesha, R. Sawant, P. Parimi, E. Gultepe, R. Bindra, V. Torchilin and S. Sridhar, Northeastern University, US
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6:00	Translation of Cancer Nanotechnology - From Bench to Bedside (Panel)	Hall D
	Session chair: Mansoor Amiji, Northeastern University
-	NCI Nanotechnology for Cancer AllianceP. Grodzinski, National Cancer Institute, US
-	Role of Nanotechnology Characterization LaboratoryS. McNeil, National Cancer Institute, US
-	Role of National Institute of Standards and TechnologyA. Plant, National Institute of Standards and Technology, US
-	Role of the Food and Drug AdministrationN. Sadrieh, Food and Drug Administration, US
	Wednesday May 10
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10:30	Cancer Nanotech - 2	Room 207
	Session chair: Mansoor Amiji, Northeastern University, US
10:30	Development of peptide conjugated Superparamagnetic Iron Oxide (SPIO) Nanoparticles for Targeted MR Imaging and Therapy of Pancreatic Cancer L. Yang, H. Mao, Z. Cao, A. Wang, X. Peng, X. Wang, P. Karna, G. Adams, Q. Yuan, C. Staley, W.C. Wood, S. Nie and X. Gao, Emory University, US
10:50	Development of Tumor Targeting Magnetic Nanoparticles for Cancer Therapy R. Ivkov, S.J. DeNardo, L.A. Miers, A. Natarajan, A.R. Foreman, C. Gruettner, G.N. Adamson and G.L. DeNardo, Triton BioSystems, Inc., US
11:10	Analysis of Magnetic Particle Capture in the Microvasculature E.P. Furlani, K.C. Ng and Y. Sahoo, University at Buffalo, US
11:30	Condensation of Therapeutic Oligodeoxynucleotides and Plasmid DNA with PPI Dendrimers and PPI-Modified Gold Nanoparticles A.M. Chen, S.K. Nair, T.T. Thomas, T.J. Thomas and H. He, Rutgers Unverisity, Newark, US
11:50	Detection of Live Breast Cancer Cells Using Carbon Nanotube Devices K. Teker, G. Cesarone, E. Wickstrom and B. Panchapakesan, Frostburg State University, US
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1:30	Nanotechnology for Drug Delivery	Room 208
	Session chair: Mansoor Amiji, Northeastern University, US
1:30	Nanotechnology for Drug Delivery: An Overview (invited overview presentation) M.M. Amiji, Northeastern University, US
2:00	The Targeted Drug Delivery of Doxorubicin W.M. Saltzman, T. Fahmy and P.M. Fong, Yale University, US
2:20	Nanoconjugates of poly(malic acid) with functional modules for drug delivery J.Y. Ljubimova, M. Fujita, B.-S. Lee, N.M. Khazenzon, S. Wachsmann-Hogiu, D.L. Farkas, K.L. Black and E. Holler, Cedars-Sinai Medical Center, US
2:40	Improved Therapeutic Efficacy of Doxorubicin-Loaded Long-Circulating Liposomes Targeted with Anti-Nuclesome Monoclonal Antibody 2C5 Against Various Tumors T.A. ElBayoumi and V.P. Torchilin, Northeastern University, US
3:00	In Vivo Tracking of Liposomes Using CT and MR Imaging J. Zheng, J. Liu, D.A. Jaffray and C. Allen, University of Toronto, CA
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4:00	Nanotech for Neurology	Room 204
	Session chair: Gabriel Silva, University of California, San Diego, US
4:00	Fluorescent Nanoparticle Quantum Dots for Targeted Neuromodulation and Bioassay (invited) T.Q. Vu, S. Golledge and S.S. Rajan, Oregon Health and Sciences University, US
4:20	Nanotechnology Contributions to Neuroscience and Neurology (invited) G.A. Silva, University of California, San Diego, US
4:40	Quantum Dot Probes for Tracking Nerve Growth Factor Ligand-Receptor Dynamics in Live Neurons (invited) S. Sundara Rajan and T.Q. Vu, Oregon Health and Science University, US
5:00	Neuroimaging Distribution of Water Molecules in Brain E. Vaganova, S. Yitzchaik, H. Ovadia, J.W. Borst, A. Visser, M. Sigalov and V. Khodorkovsky, The Hebrew University, IL
5:20	Three-Dimensional Reconstruction of the Florid Plaque in variant Creutzfeldt-Jakob Diseases M. Zubert, M. Napieralska, A. Napieralski, B. Sikorska, P. Liberski and R. Grams, Technical University of Lodz, PL
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4:00	Characterization: Drug Delivery	Room 210
	Session chair: Pierre Panine, E.S.R.F., FR and Greg Haugstad, University of Minnesota, US
4:00	Drug Eluting Coatings for Medical Devices: Multi-Method Characterization (invited) K. Wormuth and G.D. Haugstad, SurModics Inc., US (speaker biography)
4:30	Sensing and Plotting Single Molecule Binding Events with the Atomic Force Microscope W.T. Johnson, Molecular Imaging, US
4:50	Dicationic gemini surfactant gene delivery complexes contain cubic-lamellar mixed polymorphic phase M. Foldvari, S. Wettig, I. Badea, R. Verrall and M. Bagonluri, University of Saskatchewan, CA
5:10	The micro and nano scale characterization of polymer coated drug delivery stents M. Wu, M.C. Davies and C.J. Roberts, University of Nottingham & Guidant Corporation, UK
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4:00	Bio Materials and Tissues - 1	Room 203
	Session chair: Tom Webster, Brown University, US
4:00	Overview - Bio Materials and Tissues (invited overview presentation) T.J. Webster, Brown University, US
4:30	Polysaccharide based Nanoparticles and Nanoporous matrices P. Fojan, K. Schwach-Abdellaoui, K. Tommeraas, L. Gurevich and S.B. Petersen, Aalborg University, DK
4:50	In vitro human model for tumor target screening in Cancer research H. Mertsching, M. Weimer and H. Brunner, Fraunhofer Institute of Interfacial Engineering and Biotechnology, DE
5:10	Less Harmful Acidic Degradation of Poly(lactide-co-glycolide) Bone Tissue Engineering Scaffolds through Titania Nanoparticle Addition H. Liu, E.B. Slamovich and T.J. Webster, Purdue University, US
5:30	Wettability Engineering and Bioactivation of Hydroxyapatite Nanoceramics G. Rosenman and D. Aronov, Tel Aviv University, IL
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6:00	Poster Session 3 and Reception	Hall D
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	Characterization: Drug Delivery	Hall D
-	Interaction between PEO-PPO-PEO Block Copolymer and Bovine Serum Albumin by FTIR Spectroscopy C. Guo, J. Wang and H. Liu, Chinese Academy of Sciences, CN
-	Interaction between Artificial Mucin Layer and Stimuli-Responsive Nanogel Particles for the Oral Peptide Delivery Observed in Simulated Intestinal Solutions by Using Colloid Probe AFM Method H. Kamiya, M. Yoshimura, M. Tsukada, H. Ichikawa and Y. Fukumori, Tokyo University of Agriculture and Technology, JP
-	Formulation Parameters and Characterization of Drug-loaded Biodegradable Polymeric Nanoparticles B.J. Nehilla and T.A. Desai, Boston University, US
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	Drug Delivery	Hall D
-	Mitotic Inhibition by Varying the Frequency of Water Clusters B. Ahern and C. Firestone, Nanocide Technologies Corp, US
-	Development of a Novel Triblock Copolymer Therapeutic Nanoreactor A. Ranquin, C. De Vocht, W. Meier, J. Steyaert and P. Van Gelder, VUB, BE
-	Shell Cross-Linked Nanoparticle Based on Poly(e-caprolactone)-Poly(ethylene glycol) for Photosensitizer Delivery P.S. Lai, M.Y. Huang, S.J.J. Wang, C.N. Chen and M.J. Shieh, National Taiwan University, TW
-	Formulation Optimization for the Nanoparticles-in-Microsphere Hybrid Oral Delivery Systems Using Factorial Design M.D. Bhavsar, S.B. Tiwari and M.M. Amiji, Northeastern University, US
-	Cationic Nanoparticles based on pH Responsive Polyion Complexes containing Plasmid GFP DNA G. Harper and R. Gibbs, WetaScience, UK
-	Microscopic Mechanism of Sonoporation P.A. Prentice, J.M. Burns, A. Cuschieri and P.A. Campbell, University of Dundee, UK
-	Creating ‘Smart’ Delivery Systems: Double-Targeted pH-Responsive Pharmaceutical Nanocarriers R.M. Sawant, J.P. Hurley, S. Salmaso, A. Kale, E. Tolcheva, T.S. Levchenko and V.P. Torchilin, Northeastern University, US
-	A Novel Biodegradable System Based on BSA/PCL Core-shell Structured Nanofibers for Controlled Drug Delivery Y. Feng, Y.Z. Zhang, T. Yong and S. Ramakrishna, National University of Singapore, SG
-	Synergistic Release of DNA from pH Responsive Polyion Complexes (PICs) G. Harper, WetaScience, UK
-	Prospects of Anionic Nanolipoplexes Prepared by the Heating Method in Nanotherapy M.R. Mozafari, C.J. Reed and C. Rostron, Massey University, NZ
-	A review: Drug delivery by surfactants M. Nadeem and I.B. Tan, UNIVERSITI TEKNOLOGI PETRONAS, MALAYSIA, MY
-	Synthesis and Photodynamic Efficacy of PAMAM-Photosensitiser Conjugates in Vitro C.L. Peng, P.S. Lai, C.H. Chiu, C.C. Chang, T.-Y. Lai and M.J. Shieh, National Taiwan University, TW
-	Targeting Human Brain Tumor with Anti-Nucleosome Antibody 2C5-modified Liposomes in Nude Mice Model B. Gupta, T.S. Levchenko, D.A. Mongayt and V.P. Torchilin, Northeastern University, US
-	Functional Stimuli-Responsive Nanogel-particles for Oral Peptide Delivery: Preparation, Drug-Release Behaviors and in Vitro Cellular Interaction H. Ichikawa, Y. Fukumori and H. Kamiya, Kobe Gakuin University, JP
-	Construction of Enzymosomes: Optimization of Coupling Parameters C.A. Vale, M.L. Corvo, L.C.D. Martins, C.R. Marques, G. Storm, M.E.M. Cruz and M.B.F. Martins, Laboratorio Nacional de Engenharia, Tecnologia e Inovacao, IP, PT
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	Cellular and Molecular Dynamics	Hall D
-	Modeling of Cellular Communication I. Barjis, W. Samarrai, I. Augustin and J. Barjis, New York City College of Technology, US
-	Nanoscale imaging and mechanical testing of cells and tissues X. Li, University of South Carolina, US
-	Cell proliferation and differentiation on synthetic nanofibrillar surface M.A. Lodhi, G.W. Opperman and S.M. Larkin, SurModics, Inc., US
-	DNA Hybridization G. Vezzoli, New Hampshire Community Technical College, US
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	Imaging	Hall D
-	A highly sensitive fluorescent immunoassay based on avidin labeled nanocrystals K-K Sin, C.P-Y Chan, T-H Pang, M. Seydack and R. Renneberg, The Hong Kong University of Science and Technology, HK
-	Change of 7Be decay rate in exohedral and endohedral C60 fullerene A. Ray, P. Das, S.K. Saha, J.J. Das and N. Madhavan, Variable Energy Cyclotron Center, IN
-	CdSe Nanoparticles Modified with Water-soluble Terpolymers and their Application to Biomarkers H. Tsutsumi, M. Yamada and M. Yasui, Yamaguchi University, JP
-	New Applications of Nanoparticles in Cardiovascular Imaging R.R. Sharma, FAMU-FSU College of Engineering, US
-	Surface Plasmon Spectral Shifts of Functionalized Gold Nano particles for the Use in Biosensors S. Chatterjee, G. Moriarty and B. Gersten, Queens College, CUNY, US
-	The Interaction of Protein-Modified Nanodiamond with Bacterial Cells E.V. Perevedentseva, J.-S. Tu, C.-Y. Cheng, P.-H. Chung, H.-H. Chang and C.-L. Cheng, National Dong-Hwa University, TW
-	Rapid Isolation of AMI Markers using Nanomagnetic Particles Y. Haik, R. Sista, A. Qablan, C-J. Chen and S. Palanki, United Arab Emirates university, AE
-	Polymeric Magnetomicelles As a Probe for MRI Imaging: Characterization and Mri Properties R.M. Sawant, D. Nagesha, S. Sridhar and V.P. Torchilin, Northeastern University, US
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	Bio Materials	Hall D
-	Multicomponent Coatings Improve the Biocompatibility of Load-bearing Implants V.I. Chissov, I.V. Reshetov, G.A. Frank, E.A. Levashov, D.V. Shtansky, M.M. Filushin, G.D. Efremov and S.S. Sukharev, P.A.Hertzen Moscow Research Oncological Institute, RU
-	Ion Exchange Kinetics of Natural Ionic Nanoreservoirs: Bacillus subtilis Spores S. Kazakov, E. Bonvouloir, I. Gazaryan and K. Miller, Pace University, US
-	Stem cell differentiation on nano-structured carbon surfaces B. Ercan, R. Price and T.J. Webster, Purdue University, US
-	Study of Bioactive Films Using Natural Macromolecules M. Ferreira, V. Zucolotto, M. Mulato and O.N. Oliveira Jr, FFCLRP-USP, BR
-	Nanoscale deformation mechanisms of a biological nanostructured material – nacre X. Li and Z-H Xu, University of South Carolina, US
-	Nano-Structured Biodegradable Ceramics for the Treatment of Osteoporosis G. Balasundaram and T.J. Webster, Purdue University, US
-	Enzyme/DNA/alpha-ZrP Nanocomposites: DNA assisted enhancement of enzymatic activity A. Bhambhani and C.V. Kumar, University of Connecticut, US
-	Transport of Multiple Enzymes through Semipermeable Membrane and Effect of Surfactants C. Trigo, S.W. Leung, A. Bhushan, C.K. Daniels and J.C.K. Lai, Idaho State University, College of Engineering, US
-	An investigation of the composition and hierarchical order in the skeletal elements of echinoderms G. Subramanyam, R. Lakshminarayanan, S. Jegadesan and S. Valiyaveettil, National University of Singapore, SG
-	3D Microfabricated Bioreactors C.-G. Xia and N. Fang, University of Illinois at Urbana-Champaign, US
-	DNA/Cellulose hybrid nanomaterials A. Mangalam, J. Simonsen and A.S. Benight, Oregon State University, US
-	Improvement of Polycaprolactone Nanofibers Topographies: Testing the Influence in Osteoblastic Proliferation A. Martins, J. Cunha, F. Macedo, R.L. Reis and N.M. Neves, University of Minho, PT
-	In vitro testing of the penetration and permeation of nanomaterials on a artificial human skin model M. Weimer, H. Mertsching and H. Brunner, Fraunhofer Institute of Interfacial Engineering and Biotechnology, DE
-	Patterned nanofiber meshes for biomedical applications N.M. Neves, R. Campos, A. Pedro, J. Cunha, F. Macedo and R.L. Reis, University of Minho, PT
-	Increasing the Thermal Stability of Self-Assembling DNA Nanostructures by Incorporation of isoG/isoC Base Pairs K. Ho, H. Li, E.B. Roesch, C.B. Sherrill, J.R. Prudent and T.H. LaBean, Duke University, US
-	Structural Analysis of pH Responsive Peptides J. Maltby, Farfield Sensors Ltd, US
	Thursday May 11
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8:30	Medical Imaging through Nanotechnology	Room 106
	Session chair: Srinivas Iyer, Los Alamos National Laboratory, US
8:30	Preparation of Aggregation Stable Block Copolymer Nanoparticles for Simultaneous Drug Delivery and Imaging M.E. Gindy, R.K. Prud’homme, Princeton University, US
8:50	Visualization of quantum dot-electron donor conjugate uptake and processing by living cells S.J. Clarke, C.A. Hollmann and J.L. Nadeau, McGill University, CA
9:10	Synthesis and differential uptake of drug-decorated fluorescent nanoparticles by live cancer cells R.V. Rozhkov, G.M. Knudsen, J. Sturgis, A.E. Ribbe, J.P. Robinson and V.J. Davisson, Purdue University, US
9:30	Mounting proteins on metal nanoparticles: Statistical analysis of AFM images L. Gurevich, P. Fojan, R.K. Saxena and S.B. Petersen, Aalborg University, DK
9:50	Labeling of Cells with Silver and Gold Host-Guest Nanocomposites L.P. Balogh, W. Lesniak, V.A. Sinani, A.U. Bielinska, K. Sun, B.M. Nair, E. Waite, M.S.T. Kariapper and M.K. Khan, Roswell Park Cancer Institute, US
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10:00	Coffee Break	Room 106
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10:30	Bio Materials and Tissues - 2	Room 104
	Session chair: Michael Helmus, Advance Nanotech, US
10:30	Nanoscale Analysis of Bone Mineral Crystals H. Chen, C. Robinson, R.C. Shore, S.J. Brookes, J. Zhang, D.A. Smith, B.H. Clarkson and J. Kirkham, University of Michigan, US
10:50	Nano-Hydroxyapatite Coated Acetabular Cup Implant by Electrophoretic Deposition H. Zhang, J. Krajewski, Z. Zhang, T.D. Xiao and D. Reisner, Inframat Corporation, US
11:10	Enzymatically Degradable Hydrogel Nanocomposite for Bone Regeneration E. Jabbari, X. He and A.S. Sarvestani, University of South Carolina, US
11:30	Fabrication and Characterization of Polypyrrole Nanofibers and Its Application as a Tissue Engineering Scaffold R. Ng and S.-T. Yang, The Ohio State University, US
11:50	Endothelialization of lumen of tubular scaffolds fabricated by electrospinning W. He, Z.W. Ma, W.E. Teo, Y.X. Dong, T. Yong, P.A. Robless and S. Ramakrishna, National University of Singapore, SG
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1:30	Bio Materials and Tissues - 3	Room 104
	Session chair: Matthew Laudon, NSTI, US
1:30	On Chip Induced Phagocytosis for Improved Neuronal Cell Adhesion B. Van Meerbergen, T. Raemaekers, K. Winters, D. Braeken, C. Bartic, Y. Engelborghs, W. Annaert and G. Borghs, IMEC, BE
1:50	Cluster assembled nanostructured TiO2 film mediates efficient and safe retroviral gene transduction in primary adult human melanocytes for ex-vivo gene therapy R. Carbone, I. Marangi, A. Zanardi, L. Lanfrancone, S. Minucci, P.G. Pelicci, L. Giorgetti, E. Clerici, G. Bongiorno, P. Piseri and P. Milani, European Institute of Oncology, IT
2:10	Qualitative Evaluation of the Response of Human Osteoblast Cells to Nanotopography Surfaces Based on Carbon Nanotubes I. Firkowska, S. Giannona, J. Rojas-Chapana and M. Giersig, Center of Advanced European Studies and Research, DE
2:30	Increased Osteoblast Adhesion on Nano-rough Anodized Titanium and CoCrMo C. Yao, E.B. Slamovicha and T.J. Webster, Purdue University, US
2:50	Comparison of Mesenchymal Stem Cell Adhesion and Spreading on Diamond-Like Carbon (DLC), Carbon Nitride, and Nanocrystalline Diamond W.C. Clem, S. Chowdhury, V. Thomas, V.V. Konovalov, S.A. Catledge, M.T. Laugier, S.L. Bellis and Y.K. Vohra, University of Alabama at Birmingham, US

Special Symposium

Nanotechnology has the potential to have a revolutionary impact on modern medicine, not only through the development of novel diagnosis and imaging methods, but also through targeted therapies. It is universally accepted that early detection of disease is essential even before anatomic anomalies are visible. A major challenge in diagnostics in the 21^st century is to be able to determine the exact relationship between biomarkers and the clinical pathology, as well as, to be able to non-invasively detect diseases at an early stage for maximum therapeutic benefit.

Imaging, a critically important tool in life sciences is benefiting from the advances in the development of nano scale particles and systems that improve and extend the capabilities of imaging techniques. These include novel contrast agents, quantum dot markers, engineered ligands, and smart particles that enable imaging down to the cellular, and molecular scales with higher selectivity and signals that previously possible.

In future nano medical therapy, targeting and localized delivery are the key challenges. To wage an effective war against disease, we have to have the ability to selectively target the diseased cells, while saving the normal tissue from excessive burdens of drug toxicity. However, because many drugs are systemic in the delivery, the distribution of drugs in healthy organs or tissues is especially undesirable due to the potential for side effects. Consequently, systemic application of these drugs often causes severe side effects in other tissues (e.g. cardiomyopathy, neurotoxicity), which greatly limits the maximal allowable dose of the drug.

This symposium will address the potential ways in which nanotechnology can address these challenges. Distinguished speakers will summarize the current state of the art and future barriers. Contributions are also solicited in the following topics.

Journal Submissions

Journal of Nanoparticle Research

Selected Nanotech Proceedings papers will be reviewed and invited into a Special Issue of Journal of Nanoparticle Research.

For consideration into this Special Issue of Journal of Nanoparticle Research, please select the "Submit to Journal of Nanoparticle Research" button during the on-line submission procedure. Please note that you may only select a single journal during the submission process.

Topics & Application Areas

Ion Channels
Membranes
Bio Interfaces
Biocompatability
Cell Signaling Systems
RNA Synthesis
DNA Repair
Protein Structure
Protein Function
Protein Protein Interactions
Biomimetics
Immunomodulation
Nanoscale Structure
Nanoscale Properties
BioMolecular Machinery
BioMolecular Fabrication
Bio Nano Sensors
Bio Molecular Motors
Other

Symposium Coordinator

Matthew Laudon
Nano Science and Technology Institute

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Conference Proceedings

Nano Medicine

Confirmed Speakers

Symposium Sessions

Monday May 8

Tuesday May 9

Wednesday May 10

Thursday May 11

Symposium Program